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Drug Interactions with Antacids. Administration of 120 mg of fexofenadine hydrochloride (2 times; 60 mg capsule) within 15 minutes of an aluminum and magnesium containing antacid (Maalox reg; ) decreased fexofenadine AUC by 41 and C max allegra carpenter benji bamps 43. Allegra-D 24 Hour should not be taken closely in time with aluminum and magnesium containing antacids. Interactions with Fruit Juices. Fruit juices such as grapefruit, orange and apple may reduce the bioavailability and exposure of fexofenadine. This is based on the results from 3 clinical studies using histamine induced skin wheals and flares coupled with population pharmacokinetic analysis. The size of wheal and flare were significantly larger when fexofenadine hydrochloride was xia tarantallegra yesasia fashion with either grapefruit or orange juices compared to water. Based on the literature reports, the same effects may be extrapolated to other fruit juices such as apple juice. The clinical significance of these observations is unknown.

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Avoid fruit juice; especially orange, apple, or grapefruit juice. Fruit juice can make it harder for your body to absorb fexofenadine. Call your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash. If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken a cold or allergy medicine within the past few days.

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