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The rotorod accelerated gradually and smoothly from 4 to 40 rpm during each 5-minute trial. Latencies before falling are measured for three daily sessions of four trials, with an intertrial interval of 15 minutes. Whenever the mice clung to the rod without moving (passive rotation) for two complete revolutions in succession, it is considered to have fallen. Since no mouse appeared to jump deliberately, a valid estimation of motor skills could be obtained.

Quot; The new Ph. has been advised by Michael Weiss, M.Ph.M. (r), who is the Cowan-Blum Professor of Cancer Research and Professor of Biochemistry amp; Medicine in the Endocrine Division of the Department of Biochemistry. We wish Michael well as he returns to the M.

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