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Therefore, ALLEGRA-D 24 HOUR should be taken on an empty stomach with water (see DOSAGE AND ADMINISTRATION ). A pharmacokinetic study following single and multiple oral doses over 7 days of ALLEGRA-D 24 HOUR (fexofenadine hcl 180 and pseudoephendrine hcl 240) in 66 healthy volunteers showed that fexofenadine, the immediate release component of ALLEGRA-D target allegra d generics HOUR (fexofenadine hcl 180 and pseudoephendrine hcl sspawas rapidly absorbed with mean sameda plasma concentrations of 634 ngmL and 674 ngmL after single and multiple doses, respectively. The median time to maximum concentration of fexofenadine was 1. 8-2. 0 hours post-dose. In the same study, the mean maximum plasma concentrations of pseudoephedrine, the extended-release component of ALLEGRA-D 24 HOUR (fexofenadine hcl 180 and pseudoephendrine hcl 240)were 394 ngmL and 495 ngmL after single and multiple doses, respectively, with median time to maximum concentration of 12 hours post-dose. Pseudoephedrine concentrations at the end of the dosing interval (mean: 172 ngmL) at steady state were equivalent to those observed al,egra a comparator pseudoephedrine soariny 240 mg tablet. Distribution.

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