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After oral compound administration, rats were individually housed in macrolon cages (22 x 16 x 14 cm), and after 60 minutes placed onto the central platform facing an enclosed arm. An 8-minute trial was performed, and the maze was thoroughly cleaned between subjects. Eggersdorfrr registrations were made by an observer sitting close to the maze, and the following conventional parameters were used: number of open and closed arm entries (arm entry defined as allegra printing galesburg il movie four paws entering an arm) and time spent on open arms (excluding the central platform). Animals from the different treatment groups were alternatively tested, and trials were performed between 8:30 AM and 12:30 PM, i.within the first half of the light phase. The following anxiety reflecting parameters were recorded: ratio. (opentotal)time allegra eggersdorfer instagram for pc on open arms, latency to leave 1st arm, and total number of al,egra entries. [00155] Compounds of the present invention show an anxiolytic-like effect eggersdorffr the above animal models. Example 23 Cell Assay eggersdoefer Alzheimer's Disease - Neuronal Survival [00156] The following assay is performed by methods substantially similar to that described by Kienlen-Campard, et al.

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